The utility model discloses a penta-shaft linkage precise digit control radiotherapy device, comprising a C-shaped radiation source frame whose upper end is provided with a treatment head; pulleys are driven by an electrical machine for causing the radiotherapy head to conduct the B shaft rotation; the bottom face of the head frame is arranged on the rotary table of a front bed body, and the electrical machine drives the head frame to conduct the C shaft rotation via worm gears; the electrical machine drives the pulley and a lead screw to implement the X direction movement of the rotary table on the front bed body; the electrical machine drives the pulley and the lead screw to implement the Y direction movement of the radiotherapy bed on the bed body; the electrical machine can implement the Z direction lifting of the bed body on a bottom base. The penta shafts are controlled by a computer to surround the focus of the radiation source to make the penta-shaft linkage composite motion. When the patient is on proper position, the utility model can conduct the radiotherapy irradiation for the patient from multiple directions. The treating space is the full open type. The utility model is similar to a robot with the precision assembly and a horizontal machining center, and has enough accuracy and rigidity to drive radiation source with 1300kg to move; the utility model can conduct direct programming and can implement the open type treatment by using an equal center point to find the focus.